BDBM50344869 1'-pentyl-6H-spiro[benzofuro[6,5-d][1,3]dioxole-7,3'-indolin]-2'-one::CHEMBL1780061

SMILES CCCCCN1C(=O)C2(COc3cc4OCOc4cc23)c2ccccc12

InChI Key InChIKey=PHMRUZIIERITEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344869   

TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344869(1'-pentyl-6H-spiro[benzofuro[6,5-d][1,3]dioxole-7,...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344869(1'-pentyl-6H-spiro[benzofuro[6,5-d][1,3]dioxole-7,...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Homo sapiens (human) NaV1.7 expressed in HEK293 cells assessed as decrease in [14C]guanidinium influx after 2 hr by liquid scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article