BDBM50343081 CHEMBL1771216::N-hydroxy-1-(2-methoxyethyl)-4-(4-(3-(5-(4-(trifluoromethoxy)phenyl)-2H-tetrazol-2-yl)propoxy)phenylsulfonyl)piperidine-4-carboxamide

SMILES COCCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCCCn2nnc(n2)-c2ccc(OC(F)(F)F)cc2)cc1

InChI Key InChIKey=MTRATHZFTCSGDT-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50343081   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(N-hydroxy-1-(2-methoxyethyl)-4-(4-(3-(5-(4-(triflu...)
Affinity DataKi:  0.130nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(N-hydroxy-1-(2-methoxyethyl)-4-(4-(3-(5-(4-(triflu...)
Affinity DataKi:  8.70nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(N-hydroxy-1-(2-methoxyethyl)-4-(4-(3-(5-(4-(triflu...)
Affinity DataKi:  80nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(N-hydroxy-1-(2-methoxyethyl)-4-(4-(3-(5-(4-(triflu...)
Affinity DataKi:  160nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(N-hydroxy-1-(2-methoxyethyl)-4-(4-(3-(5-(4-(triflu...)
Affinity DataKi:  230nMAssay Description:Inhibition of human MMP-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(N-hydroxy-1-(2-methoxyethyl)-4-(4-(3-(5-(4-(triflu...)
Affinity DataKi:  8.60E+3nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(N-hydroxy-1-(2-methoxyethyl)-4-(4-(3-(5-(4-(triflu...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343081(N-hydroxy-1-(2-methoxyethyl)-4-(4-(3-(5-(4-(triflu...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed