BDBM50341679 4-(2-(6-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyridin-2-yl)ethyl)-6-methylpyridin-2-amine::6-(2-{6-[2-(2-amino-6-methylpyridin-4-yl)ethyl]pyridin-2-yl}ethyl)-4-methylpyridin-2-amine::CHEMBL1615291::NOS Inhibitor, 3m

SMILES Cc1cc(N)nc(CCc2cccc(CCc3cc(C)nc(N)c3)n2)c1

InChI Key InChIKey=ZMKGFXFDYMNDSP-UHFFFAOYSA-N

Data  6 KI

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50341679   

TargetNitric oxide synthase, brain(Human)
University of California Irvine

LigandPNGBDBM50341679(CHEMBL1615291 | NOS Inhibitor, 3m | 6-(2-{6-[2-(2-...)
Affinity DataKi:  195nMAssay Description:Inhibition assay using nitric oxide synthases.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341679(CHEMBL1615291 | NOS Inhibitor, 3m | 6-(2-{6-[2-(2-...)
Affinity DataKi:  195nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Human)
University of California Irvine

LigandPNGBDBM50341679(CHEMBL1615291 | NOS Inhibitor, 3m | 6-(2-{6-[2-(2-...)
Affinity DataKi:  1.26E+4nMAssay Description:Inhibition assay using nitric oxide synthases.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341679(CHEMBL1615291 | NOS Inhibitor, 3m | 6-(2-{6-[2-(2-...)
Affinity DataKi:  1.26E+4nMAssay Description:Inhibition of mouse macrophage recombinant iNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
University of California Irvine

LigandPNGBDBM50341679(CHEMBL1615291 | NOS Inhibitor, 3m | 6-(2-{6-[2-(2-...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition assay using nitric oxide synthases.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341679(CHEMBL1615291 | NOS Inhibitor, 3m | 6-(2-{6-[2-(2-...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)