BDBM50341678 6,6'-(2,2'-(5-Amino-1,3-phenylene)bis(ethane-2,1diyl))-bis(4-methylpyridin-2-amine)::6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]bis(4-methylpyridin-2-amine)::CHEMBL1615292::NOS Inhibitor, 3n

SMILES Cc1cc(N)nc(CCc2cc(N)cc(CCc3cc(C)cc(N)n3)c2)c1

InChI Key InChIKey=WZQDEYWNUPXXDO-UHFFFAOYSA-N

Data  9 KI

PDB links: 9 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50341678   

TargetNitric oxide synthase, brain(Human)
University of California Irvine

LigandPNGBDBM50341678(6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]b...)
Affinity DataKi:  85nMAssay Description:Inhibition assay using nitric oxide synthases.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, brain(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50341678(6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]b...)
Affinity DataKi:  85nMAssay Description:Inhibition of rat nNOSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, brain(Rat)
University of California

Curated by ChEMBL
LigandPNGBDBM50341678(6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]b...)
Affinity DataKi:  85nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, inducible(Human)
University of California Irvine

LigandPNGBDBM50341678(6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]b...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition assay using nitric oxide synthases.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50341678(6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]b...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of mouse iNOSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
University of California

Curated by ChEMBL
LigandPNGBDBM50341678(6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]b...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of mouse macrophage recombinant iNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
University of California Irvine

LigandPNGBDBM50341678(6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]b...)
Affinity DataKi:  4.95E+3nMAssay Description:Inhibition assay using nitric oxide synthases.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50341678(6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]b...)
Affinity DataKi:  4.95E+3nMAssay Description:Inhibition of bovine eNOSMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
University of California

Curated by ChEMBL
LigandPNGBDBM50341678(6,6'-[(5-aminobenzene-1,3-diyl)diethane-2,1-diyl]b...)
Affinity DataKi:  4.95E+3nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)