BDBM50340520 5,5-dimethyl-1-(quinolin-4-ylmethyl)-3-(4-(trifluoromethylsulfonyl)phenyl)imidazolidine-2,4-dione::CHEMBL1762154

SMILES CC1(C)N(Cc2ccnc3ccccc23)C(=O)N(C1=O)c1ccc(cc1)S(=O)(=O)C(F)(F)F

InChI Key InChIKey=WXNMKLZXAKKCON-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340520   

TargetInsulin-like growth factor 1 receptor(Human)
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50340520(5,5-dimethyl-1-(quinolin-4-ylmethyl)-3-(4-(trifluo...)
Affinity DataIC50: 460nMAssay Description:Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in SF21 cells by time resolved-fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)