BDBM50340250 (6S)-6,15,15,18-tetramethyl-17-oxo-2,3,4,5,6,7,14,15,16,17-decahydro-1H-8,12-(metheno)[1,4,9]triazacyclotetradecino[9,8-a]indole-9-carboxamide::CHEMBL1738703

SMILES C[C@H]1CNCCCc2c(C)c3c(CC(C)(C)CC3=O)n2-c2ccc(C(N)=O)c(N1)c2

InChI Key InChIKey=DGOVAFNEOBXFEF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340250   

TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50340250((6S)-6,15,15,18-tetramethyl-17-oxo-2,3,4,5,6,7,14,...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50340250((6S)-6,15,15,18-tetramethyl-17-oxo-2,3,4,5,6,7,14,...)
Affinity DataIC50: 110nMAssay Description:Inhibition of HSP90alpha after 3 hrs by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50340250((6S)-6,15,15,18-tetramethyl-17-oxo-2,3,4,5,6,7,14,...)
Affinity DataIC50: 110nMAssay Description:Binding affinity to HSP90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed