BDBM50339888 1-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperidin-3-yl)-3-ethyl-1H-benzo[d]imidazol-2(3H)-one::CHEMBL1761282

SMILES CCn1c2ccccc2n(C2CCCN(C2)c2nccc(n2)-c2cc3ccccc3o2)c1=O

InChI Key InChIKey=NXTBLPPTZRPJCA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50339888   

TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339888(1-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperidin-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50339888(1-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperidin-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50339888(1-(1-(4-(benzofuran-2-yl)pyrimidin-2-yl)piperidin-...)
Affinity DataIC50: 10nMAssay Description:Reversible inhibition of human FAAHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed