BDBM50338197 5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrimidin-2-amine::5-(7-Methanesulfonyl-2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-ylamine::CHEMBL1684984

SMILES CS(=O)(=O)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1

InChI Key InChIKey=JEGHXKRHKHPBJD-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50338197   

LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: 36nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KC2alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of PI3KC2betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Vps34More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of P13Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed