BDBM50322742 CHEMBL1173694::N-(2-(1H-benzo[d]imidazol-2-yl)ethyl)-2-(2-bromophenoxy)acetamide::N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenoxy)acetamide

SMILES Brc1ccccc1OCC(=O)NCCc1nc2ccccc2[nH]1

InChI Key InChIKey=XWFRNTHGPRGCNS-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50322742   

TargetCruzipain(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50322742(N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenox...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine expressed in Escherichia coli SG13009 using Z-FR-AMC as substrate after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50322742(N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenox...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50322742(N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenox...)
Affinity DataIC50: 800nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50322742(N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenox...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain assessed as Z-Phe-Arg-aminomethylcoumarin cleavage by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50322742(N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenox...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed