BDBM50320082 1-(4-Amino-2-butyl-1H-imidazo-[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol::CHEMBL1082983
SMILES CCCCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O
InChI Key InChIKey=GITVQUOQRHRGQQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50320082
Affinity DataEC50: 8.58nMAssay Description:Agonist activity at human TLR7 expressed in NF-kappaB-stimulated HEK293 cells assessed as induction of secreted alkaline phosphatase expression by re...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at human TLR8 transfected in HEK cells assessed as NFkappaB induction after 24 hrs by specific secreted alkaline phosphatase gene as...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at human TLR7 transfected in HEK cells assessed as NFkappaB induction after 24 hrs by specific secreted alkaline phosphatase gene as...More data for this Ligand-Target Pair
Affinity DataEC50: 8.60nMAssay Description:Agonist activity at TLR7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells assessed as activation of NFkappaB incubated for 18 to 24 hrs by SEAP reporter gene based as...More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as activation of NFkappaB incubated for 18 to 24 hrs by SEAP reporter gene based as...More data for this Ligand-Target Pair