BDBM50319157 4-Cyano-8-methoxy-3-methyl-1-propyl-imidazo[1,5-a]pyrido-[3,2-e]pyrazine::CHEMBL1086265

SMILES CCCc1nc(C)c2c(nc3ccc(OC)nc3n12)C#N

InChI Key InChIKey=GQYPTVVKCVYXLX-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50319157   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Biotie Therapies

Curated by ChEMBL

LigandBDBM50319157(4-Cyano-8-methoxy-3-methyl-1-propyl-imidazo[1,5-a]...)Copy SMILESCopy InChI

Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

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