BDBM50316349 2-(5-{[(2S)-2-Amino-3-phenylpropyl]oxy}pyridin-3-yl)-8,9-dimethoxybenzo[c]-2,7-naphthyridin-4-amine::2-(5-{[(2S)-2-amino-3-phenylpropyl]oxy}pyridin-3-yl)-8,9-dimethoxybenzo[c][2,7]naphthyridin-4-amine::CHEMBL1097602

SMILES COc1cc2ncc3c(N)nc(cc3c2cc1OC)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1

InChI Key InChIKey=XNXUJUXYVTYIGP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50316349   

Target3-phosphoinositide-dependent protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316349(2-(5-{[(2S)-2-Amino-3-phenylpropyl]oxy}pyridin-3-y...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316349(2-(5-{[(2S)-2-Amino-3-phenylpropyl]oxy}pyridin-3-y...)
Affinity DataIC50: 261nMAssay Description:Inhibition of AKTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316349(2-(5-{[(2S)-2-Amino-3-phenylpropyl]oxy}pyridin-3-y...)
Affinity DataIC50: 107nMAssay Description:Inhibition of p70S6KMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed