BDBM50314705 (2R,4E)-2-[(naphthalen-2-ylcarbonyl)amino]-5-phenylpent-4-enoic acid::(R,)-2-(2-naphthamido)-5-phenylpent-4-enoic acid::CHEMBL1090714

SMILES OC(=O)[C@@H](C\C=C\c1ccccc1)NC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=OOTIJYFZZMIZHN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314705   

LigandPNGBDBM50314705((R,)-2-(2-naphthamido)-5-phenylpent-4-enoic acid |...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Pin1 by whole cell assayMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50314705((R,)-2-(2-naphthamido)-5-phenylpent-4-enoic acid |...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed