BDBM50304974 (S)-2-chloro-4-((2-methylbenzyl)(1-(methylsulfonyl)pyrrolidin-3-yl)amino)benzonitrile::2-chloro-4-{(2-methylbenzyl)[(3S)-1-(methylsulfonyl)pyrrolidin-3-yl]amino}benzonitrile::CHEMBL601500

SMILES Cc1ccccc1CN([C@H]1CCN(C1)S(C)(=O)=O)c1ccc(C#N)c(Cl)c1

InChI Key InChIKey=OTRAFCFYTZJLKH-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50304974   

TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304974(2-chloro-4-{(2-methylbenzyl)[(3S)-1-(methylsulfony...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at PR in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304974(2-chloro-4-{(2-methylbenzyl)[(3S)-1-(methylsulfony...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human ERG by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304974(2-chloro-4-{(2-methylbenzyl)[(3S)-1-(methylsulfony...)
Affinity DataIC50: 16nMAssay Description:Inhibition of PRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304974(2-chloro-4-{(2-methylbenzyl)[(3S)-1-(methylsulfony...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304974(2-chloro-4-{(2-methylbenzyl)[(3S)-1-(methylsulfony...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed