BDBM50304144 5-NITROINDAZOLE::5-Nitro-1H-indazole::CHEMBL165372

SMILES [O-][N+](=O)c1ccc2[nH]ncc2c1

InChI Key InChIKey=WSGURAYTCUVDQL-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50304144   

TargetAmine oxidase [flavin-containing] B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50304144(5-Nitro-1H-indazole | 5-NITROINDAZOLE | CHEMBL1653...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNitric oxide synthase, brain(Human)
Uned

Curated by ChEMBL
LigandPNGBDBM50304144(5-Nitro-1H-indazole | 5-NITROINDAZOLE | CHEMBL1653...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of NOS1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50304144(5-Nitro-1H-indazole | 5-NITROINDAZOLE | CHEMBL1653...)
Affinity DataKi:  5.60E+5nMAssay Description:Inhibition of human N-terminal His6-tagged PDE10A2 catalytic domain expressed in Escherichia coli BL21(DE3) RIL cells using 3',5'-cGMP as substrate b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50304144(5-Nitro-1H-indazole | 5-NITROINDAZOLE | CHEMBL1653...)
Affinity DataKi:  5.60E+5nMAssay Description:Inhibition of human N-terminal His6-tagged PDE10A2 catalytic domain expressed in Escherichia coli BL21(DE3) RIL cells using 3',5'-cGMP as substrate b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed