BDBM50300465 (+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid::5-(biphenyl-4-yl)-3-hydroxypentanoic acid::CHEMBL572982

SMILES OC(CCc1ccc(cc1)-c1ccccc1)CC(O)=O

InChI Key InChIKey=ILGSIIFHQGOKKV-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50300465   

TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrilysin(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human recombinant ACEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage metalloelastase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant MMP12More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase 3(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of human recombinant MMP13More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human recombinant ACEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 3.66E+4nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrilysin(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP7More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Gsk Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50300465(5-(biphenyl-4-yl)-3-hydroxypentanoic acid | (+/-)5...)
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed