BDBM50299249 1,10-Dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde::CHEMBL583972::US8481586, 3

SMILES O=Cc1c[nH]c2c1ccc1c3ccccc3[nH]c21

InChI Key InChIKey=VWNCOFUKBTYAON-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50299249   

TargetSerine/threonine-protein kinase pim-1(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(US8481586, 3 | CHEMBL583972 | 1,10-Dihydropyrrolo[...)
Affinity DataIC50: 120nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(US8481586, 3 | CHEMBL583972 | 1,10-Dihydropyrrolo[...)
Affinity DataIC50: 510nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase pim-3(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(US8481586, 3 | CHEMBL583972 | 1,10-Dihydropyrrolo[...)
Affinity DataIC50: 10nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSerine/threonine-protein kinase pim-3(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(US8481586, 3 | CHEMBL583972 | 1,10-Dihydropyrrolo[...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Pim-3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(US8481586, 3 | CHEMBL583972 | 1,10-Dihydropyrrolo[...)
Affinity DataIC50: 510nMAssay Description:Inhibition of Pim-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(US8481586, 3 | CHEMBL583972 | 1,10-Dihydropyrrolo[...)
Affinity DataIC50: 120nMAssay Description:Inhibition of Pim-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(US8481586, 3 | CHEMBL583972 | 1,10-Dihydropyrrolo[...)
Affinity DataIC50: 510nMAssay Description:Inhibition of human GST fused Pim2 expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(US8481586, 3 | CHEMBL583972 | 1,10-Dihydropyrrolo[...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human GST fused Pim1 expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(US8481586, 3 | CHEMBL583972 | 1,10-Dihydropyrrolo[...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human GST fused Pim3 expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(US8481586, 3 | CHEMBL583972 | 1,10-Dihydropyrrolo[...)
Affinity DataIC50: 510nMAssay Description:Inhibition of human Pim2 using RSRHSSYPAGT as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(US8481586, 3 | CHEMBL583972 | 1,10-Dihydropyrrolo[...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human Pim3 using RSRHSSYPAGT as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299249(US8481586, 3 | CHEMBL583972 | 1,10-Dihydropyrrolo[...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human Pim1 using RSRHSSYPAGT as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed