BDBM50285033 CHEMBL4165354

SMILES COc1ccc(Cc2nnc3sc(nn23)-c2cc3ccccc3[nH]2)cc1

InChI Key InChIKey=ZXLRTUDCUYHDLP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50285033   

TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50285033(CHEMBL4165354)
Affinity DataIC50: 190nMAssay Description:Inhibition of human GST-tagged c-MET using KKKSPGEYVNIEFG as substrate preincubated for 20 mins followed by [gamma-33P]ATP addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50285033(CHEMBL4165354)
Affinity DataIC50: 3.33E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50285033(CHEMBL4165354)
Affinity DataIC50: 79nMAssay Description:Inhibition of GST-tagged human c-MET preincubated for 20 mins followed by [33P]-ATP addition and measured after 2 hrs by Hot-Spot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed