BDBM50272952 CHEMBL4126054

SMILES NC(=O)c1ccc(Oc2cccc(c2)C(N)=O)cc1

InChI Key InChIKey=PMOXYDXLQIUWHL-UHFFFAOYSA-N

Data  9 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50272952   

TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50: 513nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50: 510nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50: 480nMAssay Description:Inhibition of C-terminal his-tagged human PARP10 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of N-terminal his-tagged human PARP15 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of N-terminal his-tagged human PARP14 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of N-terminal his-tagged human TNKS1 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of N-terminal his-tagged human TNKS2 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal his-tagged human PARP1 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of N-terminal his-tagged human PARP2 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails
PubMed