BDBM50267750 CHEMBL1078685
SMILES N#Cc1cc(ccn1)-c1n[nH]c(n1)-c1ccncc1
InChI Key InChIKey=UBVZQGOVTLIHLH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50267750
Affinity DataIC50: 15nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of bovine milk xanthine oxidoreductase assessed as reduction in conversion of xanthine to uric acid by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Inhibition of bovine milk xanthine oxidase using xanthine as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Federal University of Parana
Curated by ChEMBL
Federal University of Parana
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in human HEK293-A cells membrane vesicles assessed inhibition of ABCG2-mediated urate transport activi...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Competitive inhibition of bovine milk xanthine oxidoreductase assessed as reduction in uric acid formation by spectrophotometric assayMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Human)
West China Hospital of Sichuan University
Curated by ChEMBL
West China Hospital of Sichuan University
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair