BDBM50264813 (2R)-3-({[4-[(PYRIDIN-4-YL)PHENYL]-THIEN-2-YL}CARBOXAMIDO)(PHENYL)PROPANOIC ACID::(R)-3-phenyl-3-(4-(4-(pyridin-4-yl)phenyl)thiophene-2-carboxamido)propanoic acid::CHEMBL508461

SMILES OC(=O)C[C@@H](NC(=O)c1cc(cs1)-c1ccc(cc1)-c1ccncc1)c1ccccc1

InChI Key InChIKey=VMTJQZUZINLEKC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50264813   

TargetMatrix metalloproteinase-9(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264813((R)-3-phenyl-3-(4-(4-(pyridin-4-yl)phenyl)thiophen...)
Affinity DataIC50: 980nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage metalloelastase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264813((R)-3-phenyl-3-(4-(4-(pyridin-4-yl)phenyl)thiophen...)
Affinity DataIC50: 14nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264813((R)-3-phenyl-3-(4-(4-(pyridin-4-yl)phenyl)thiophen...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264813((R)-3-phenyl-3-(4-(4-(pyridin-4-yl)phenyl)thiophen...)
Affinity DataIC50: 390nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264813((R)-3-phenyl-3-(4-(4-(pyridin-4-yl)phenyl)thiophen...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase 3(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50264813((R)-3-phenyl-3-(4-(4-(pyridin-4-yl)phenyl)thiophen...)
Affinity DataIC50: 270nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails Article
PubMed