BDBM50262255 CHEMBL4096246

SMILES CN1CCC(CC1)NC(=O)c1ccc(Nc2cc(NCc3ccccc3)c(cn2)C(N)=O)cc1

InChI Key InChIKey=NYSLPKXXILEKDL-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262255   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50262255(CHEMBL4096246)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluorescent labelled IPTSPITTTYFFFKKK peptide as substrate after 60 mins by caliper assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In DepthDetails Article
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TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50262255(CHEMBL4096246)Copy SMILESCopy InChI

Affinity DataIC50: 2nMAssay Description:Inhibition of JAK3 (unknown origin) by caliper assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In DepthDetails Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL