BDBM50258266 CHEMBL4088107

SMILES CCC(NC(=O)c1cnn2cc(C)cnc12)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=CXEGBNQZVKLHTO-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258266   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258266(CHEMBL4088107)
Affinity DataIC50: 53nMAssay Description:Inhibition of PDE2A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50258266(CHEMBL4088107)
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant human FLAG-tagged PDE2A3 expressed in sf21 cells using [3H]cGMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)