BDBM50252739 CHEMBL494072::N-Cyclopropyl-4-methyl-3-(2-((2-(4-morpholinyl)ethyl)amino)-6-quinazolinyl)benzamide::N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide

SMILES Cc1ccc(cc1-c1ccc2nc(NCCN3CCOCC3)ncc2c1)C(=O)NC1CC1

InChI Key InChIKey=MNEXDVSJIUQQRH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50252739   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 10.5nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 122nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 162nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 629nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 788nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethy...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed