BDBM50252622 CHEMBL4070389

SMILES OC(=O)c1cccc(NC(=O)CCNC(=O)CCNCc2ccc(c(Cl)c2)-c2ccccc2)c1

InChI Key InChIKey=NZDQDPKZQDWCOF-UHFFFAOYSA-N

Data  1 KI  5 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50252622   

TargetCasein kinase II subunit alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataIC50: 370nMAssay Description:Inhibition of CK2alpha (unknown origin) using RRRADDSDDDD as substrate after 40 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase II subunit alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataKd:  320nMAssay Description:Binding affinity to human CK2alpha expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase II subunit alpha/beta(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataKd:  310nMAssay Description:Binding affinity to CK2alpha/beta (unknown origin) expressed in Escherichia coli BL21(DE3) by ITCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase II subunit alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataKd:  320nMAssay Description:Binding affinity to CK2alpha (unknown origin) by ITCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase II subunit alpha/beta(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataIC50: 670nMAssay Description:Inhibition of CK2alpha/beta (unknown origin) expressed in Escherichia coli BL21(DE3) using RRRADDSDDDD as substrate after 40 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase II subunit alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant human CK2alpha (1 to 336 residues) expressed in Escherichia coli BL21 (DE3) using RRADDSDDDD as substrate incubated for 10 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase II subunit alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataIC50: 370nMAssay Description:Inhibition of human CK2alpha using RRRDDDSDDD peptide as substrate preincubated for 40 mins and measured after 70 mins in the presence of ATP by ADP ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCasein kinase II subunit alpha 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataIC50: 370nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCasein kinase II subunit alpha 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50252622(CHEMBL4070389)
Affinity DataKi:  320nMAssay Description:Binding affinity to CK2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed