BDBM50241209 CHEMBL4101660

SMILES CCc1cc2nc(c(C#N)c(N3CCC(C)(O)C3)c2[nH]1)C(F)(F)F

InChI Key InChIKey=PSWIJUOHBAWLCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241209   

TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241209(CHEMBL4101660)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMed
TargetKetohexokinase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241209(CHEMBL4101660)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KHK expressed in Escherichia coli BL21(DE3) using fructose as substrate incubated for 30 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2019
Entry Details Article
PubMed