BDBM50241112 2-(2-Amino-phenylamino)-10,11-dihydro-dibenzo[a,d]cyclohepten-5-one::CHEMBL218962

SMILES Nc1ccccc1Nc1ccc2c(CCc3ccccc3C2=O)c1

InChI Key InChIKey=VMANCBCSTYKPPA-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50241112   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50241112(2-(2-Amino-phenylamino)-10,11-dihydro-dibenzo[a,d]...)
Affinity DataIC50: 100nMAssay Description:Inhibition of p38alpha MAPK by cell-free enzyme immunosorbent assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50241112(2-(2-Amino-phenylamino)-10,11-dihydro-dibenzo[a,d]...)
Affinity DataIC50: 50nMAssay Description:Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50241112(2-(2-Amino-phenylamino)-10,11-dihydro-dibenzo[a,d]...)
Affinity DataIC50: 104nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 11/12/13/14(Human)
University of Zagreb

Curated by ChEMBL
LigandPNGBDBM50241112(2-(2-Amino-phenylamino)-10,11-dihydro-dibenzo[a,d]...)
Affinity DataIC50: 50nMAssay Description:Inhibition of MAPK p38 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)