BDBM50240538 CHEMBL57481::Isoquinolin-5-ol

SMILES Oc1cccc2cnccc12

InChI Key InChIKey=CSNXUYRHPXGSJD-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240538   

TargetMAP kinase-activated protein kinase 2(Human)
Bristol Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50240538(Isoquinolin-5-ol | CHEMBL57481)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of human recombinant MK2 expressed in Escherichia coli BL21(DE3) after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeregrin(Human)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50240538(Isoquinolin-5-ol | CHEMBL57481)
Affinity DataKd:  1.70E+5nMAssay Description:Binding affinity to recombinant GST-tagged human BRPF1 expressed in Escherichia coli BL21 (DE3) after 1 hr by qPCR-based BromoScan assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)