BDBM50236535 CHEMBL1231132

SMILES CN(C)C(=O)c1ccc(cc1)S(=O)(=O)c1ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c1

InChI Key InChIKey=DTDZLJHKVNTQGZ-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50236535   

LigandPNGBDBM50236535(CHEMBL1231132)
Affinity DataIC50: 41nMAssay Description:Inhibition of PDHK1 in human PC3 cells assessed as decrease in phosphorylation of E1alpha subunit at serine 293 residue after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50236535(CHEMBL1231132)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50236535(CHEMBL1231132)
Affinity DataEC50:  80nMAssay Description:Inhibition of PDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50236535(CHEMBL1231132)
Affinity DataIC50: 80nMAssay Description:Inhibition of E2-activated human PDHK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50236535(CHEMBL1231132)
Affinity DataIC50: 80nMAssay Description:Inhibition of E2-activated human PDHK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed