BDBM50232053 CHEMBL271741::N-(4-amino-biphenyl-3-yl)-benzamide::N-(4-aminobiphenyl-3-yl)benzamide

SMILES Nc1ccc(cc1NC(=O)c1ccccc1)-c1ccccc1

InChI Key InChIKey=ZWLFHHHQRUYIBT-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50232053   

TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 24 hrs followed by 1 hr reaction with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant HDAC2 preincubated for 1 hr with substrate by protease coupled end-point assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 11(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC11More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 60nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 780nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC7More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant HDAC1 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 5 mins measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 3 hrs measured after 35 mins by spectroflu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50232053(N-(4-aminobiphenyl-3-yl)benzamide | N-(4-amino-bip...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC2 using Boc-L-Lys (Ac)-AMC as substrate preincubated with compound for 24 hrs measured after 35 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed