BDBM50216682 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine::1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine::5-(2-methylpiperazine-1-sulfonyl)isoquinoline::CHEMBL323556::cid_3542

SMILES CC1CNCCN1S(=O)(=O)c1cccc2cnccc12

InChI Key InChIKey=BDVFVCGFMNCYPV-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50216682   

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50216682(cid_3542 | 1-(5-Isoquinolinesulfonyl)-2-methylpipe...)
Affinity DataIC50: 6.64E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50216682(cid_3542 | 1-(5-Isoquinolinesulfonyl)-2-methylpipe...)
Affinity DataIC50: 100nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50216682(cid_3542 | 1-(5-Isoquinolinesulfonyl)-2-methylpipe...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of cAMP-dependent protein kinase (PKA).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50216682(cid_3542 | 1-(5-Isoquinolinesulfonyl)-2-methylpipe...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of protein kinase C (PKC)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50216682(cid_3542 | 1-(5-Isoquinolinesulfonyl)-2-methylpipe...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of ATP from protein kinase A (PKA)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50216682(cid_3542 | 1-(5-Isoquinolinesulfonyl)-2-methylpipe...)
Affinity DataKi:  6.00E+3nMAssay Description:Displacement of ATP from protein kinase C (PKC)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed