BDBM50208228 1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-ylamino)-2-oxoethylphosphonic acid::CHEMBL387130

SMILES OP(O)(=O)C(C(=O)Nc1ccc2ccccc2c1)c1csc2ccc(Cl)cc12

InChI Key InChIKey=HUJXISJLAPAFBO-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50208228   

TargetChymase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50208228(1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetChymase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50208228(1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...)
Affinity DataKi:  36nMAssay Description:Inhibition of human skin chymaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCathepsin G(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50208228(1-(5-chlorobenzo[b]thiophen-3-yl)-2-(naphthalen-2-...)
Affinity DataKi:  9.50E+3nMAssay Description:Inhibition of human neutrophil Cat GMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed