BDBM50205947 (2R)-1-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)-N-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)pyrrolidine-2-carboxamide::CHEMBL376632::N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE

SMILES Cc1cc(nc(n1)-n1ccnc1)N1CCC[C@@H]1C(=O)NCCc1ccc2OCOc2c1

InChI Key InChIKey=LBCGUKCXRVUULK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205947   

TargetNitric oxide synthase, inducible(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50205947(N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZO...)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of cytokine-induced iNOS expressed in human A172 cells assessed as inhibition of NO formationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed