BDBM50204516 6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid::6-[2-(7-phenylheptanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acid::CHEMBL219942

SMILES OC(=O)c1cccc(n1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1

InChI Key InChIKey=DZMRAEAGLIEJDZ-UHFFFAOYSA-N

Data  8 KI  8 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50204516   

TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataIC50: 100nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetNeutral cholesterol ester hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataIC50: 100nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataKi:  10.3nMpH: 7.4Assay Description:Inhibition of rat FAAH expressed in Escherichia coli at pH 7.4More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataKi:  10.4nMpH: 7.5Assay Description:Inhibition of FAAH at pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataKi:  14.5nMpH: 8.0Assay Description:Inhibition of rat FAAH expressed in Escherichia coli at pH 8.0More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataKi:  20nMpH: 9.0Assay Description:Inhibition of FAAH at pH 9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataKi:  20nMAssay Description:Inhibition of rat FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataKi:  20nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataKi:  26nMAssay Description:Inhibition of human FAAH expressed in COS7 cells by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204516(6-(2-(7-phenylheptanoyl)oxazol-5-yl)picolinic acid...)
Affinity DataKi:  26nMAssay Description:Inhibition of human recombinant FAAH expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed