BDBM50174412 9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole::9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole9-OCH3-E::9-methoxy ellipticine::9-methoxyellipticine::CHEMBL19954::O-methylellipticine::cid_72512

SMILES COc1ccc2[nH]c3c(C)c4ccncc4c(C)c3c2c1

InChI Key InChIKey=BKRMCDAOAQWNTG-UHFFFAOYSA-N

Data  12 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50174412   

TargetX-box-binding protein 1(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetToll-like receptor 3(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of TLR3 in HEK-Blue hTLR3 assessed as inhibition of poly (I:C) induced SEAP signallingMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataIC50: 5.42E+5nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlucocorticoid receptor(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Cnrs Umr-8113

Curated by ChEMBL
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProbable global transcription activator SNF2L2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataEC50:  3.38E+3nMMore data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetDelta-type opioid receptor(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataEC50: >6.47E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetMelanocortin receptor 4(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataEC50: >8.93E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetOrotidine 5'-phosphate decarboxylase(Aspergillus niger)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataEC50: >5.97E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataIC50: 5.13E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataEC50: >2.60E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataIC50: 5.13E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
TargetNeutrophil cytosol factor 1 [S99G](Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataIC50: 1.78E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataIC50: 5.40E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataIC50: 2.47E+4nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataIC50: 2.68E+4nMAssay Description:Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay
LigandPNGBDBM50174412(CHEMBL19954 | cid_72512 | 9-Methoxy-5,11-dimethyl-...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...More data for this Ligand-Target Pair
In DepthDetails
PCBioAssay