BDBM50169892 3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl]-pyridin-2-ylamino}-propan-1-ol::CHEMBL191336

SMILES OCCCNc1cc(ccn1)-c1ncnc(Nc2cccc(Cl)c2)n1

InChI Key InChIKey=AAYPLLWGPJQWCC-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50169892   

TargetCasein kinase I isoform alpha/delta/epsilon/gamma-1/gamma-2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition of Casein kinase IMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 126nMAssay Description:Inhibition of CDK7/cyclin HMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Platelet derived growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration of compound against CDK2/cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 356nMAssay Description:Inhibition of CDK6/cyclin D3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK5/p35More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 308nMAssay Description:Inhibition of CDK4/cyclin D1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKB betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Fibroblast growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 21nMAssay Description:Inhibition of cyclin dependent kinase CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50169892(3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed