BDBM50166350 CHEMBL3798631

SMILES CC(NC(=O)c1ccc2[nH]nc(-c3ccncc3)c2c1)c1cccc(Cl)c1

InChI Key InChIKey=ZEKIJJKMJBIZDL-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50166350   

TargetMitogen-activated protein kinase 3(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 154nMAssay Description:Inhibition of human recombinant GST-tagged ERK1 expressed in Escherichia coli using ser/thr 3 Peptide as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant GST-tagged ERK2 expressed in Escherichia coli using ser/thr 3 Peptide as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-MET (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IGF1R (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ALK (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FLT1 (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of KDR (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RET (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ERBB2 (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-Src (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-A receptor 2(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EPHA2 (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FGFR1 (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Green Valley Research Institute

Curated by ChEMBL
LigandPNGBDBM50166350(CHEMBL3798631)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL (unknown origin) by Z-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed