BDBM50164534 CHEMBL3800287

SMILES CC1Sc2ccc(cc2NC1=O)C(=O)NO

InChI Key InChIKey=GIAXUWZVCYGXKO-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50164534   

TargetHistone deacetylase 1(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164534(CHEMBL3800287)
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164534(CHEMBL3800287)
Affinity DataIC50: 970nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164534(CHEMBL3800287)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164534(CHEMBL3800287)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164534(CHEMBL3800287)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human HDAC6 using Z(Tfa)Lys-AMC as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164534(CHEMBL3800287)
Affinity DataIC50: 970nMAssay Description:Inhibition of human HDAC8 using Fluor de Lys as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164534(CHEMBL3800287)
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of human HDAC1 (1 to 482 reidue) expressed in sf9 cells using Fluor de Lys as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164534(CHEMBL3800287)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of Schistosoma mansoni HDAC8 using Fluor de Lys as substrate by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)