BDBM50159140 CHEMBL3785648

SMILES CCc1c([nH]c(C)c1C(C)=O)C(=O)NC

InChI Key InChIKey=LCSLEHAEHBSCSA-UHFFFAOYSA-N

Data  9 Kd

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50159140   

TargetBromodomain-containing protein 4(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  6.80E+3nMAssay Description:Binding affinity to partial length human BRD4 bromodomain 1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  3.00E+4nMAssay Description:Binding affinity to partial length human BRPF1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCREB-binding protein(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  1.81E+4nMAssay Description:Binding affinity to human His-Tev tagged CBP expressed in bacterial expression system incubated for 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone acetyltransferase p300(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  2.26E+4nMAssay Description:Binding affinity to human His-Tev tagged EP300 expressed in bacterial expression system incubated for 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  2.40E+4nMAssay Description:Binding affinity to BRD4 bromo domain 1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  2.30E+4nMAssay Description:Binding affinity to BRPF1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCREB-binding protein(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  1.80E+4nMAssay Description:Binding affinity to CBP (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCREB-binding protein(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  1.81E+4nMAssay Description:Binding affinity to CBP (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetHistone acetyltransferase p300(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  2.26E+4nMAssay Description:Binding affinity to P300 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails
PubMed