BDBM50158615 Ischemin

SMILES Cc1cc(\N=N\c2cc(c(C)cc2C)S(O)(=O)=O)c(N)cc1O

InChI Key InChIKey=UUECJWRVDTUDCB-UHFFFAOYSA-N

Data  2 KI  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50158615   

TargetCREB-binding protein(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50158615(Ischemin)
Affinity DataKd:  1.96E+4nMAssay Description:Binding affinity to CBP bromodomain (unknown origin) by fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCREB-binding protein(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50158615(Ischemin)
Affinity DataKd:  1.90E+4nMAssay Description:Binding affinity to CBP bromodomain (unknown origin) assessed as dissociation constant by tryptophan fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50158615(Ischemin)
Affinity DataKi:  1.09E+4nMAssay Description:Inhibition of BRD4 BD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50158615(Ischemin)
Affinity DataKi:  1.97E+4nMAssay Description:Inhibition of BRD4 BD2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed