BDBM50157884 6-(2-Mercapto-acetylamino)-hexanoic acid phenylamide::6-(2-mercaptoacetamido)-N-phenylhexanamide::CHEMBL178727

SMILES SCC(=O)NCCCCCC(=O)Nc1ccccc1

InChI Key InChIKey=ICMLRCZXRBTKLJ-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50157884   

TargetHistone deacetylase 8(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50157884(6-(2-Mercapto-acetylamino)-hexanoic acid phenylami...)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of human HDAC8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Blood fluke)
Washington University

Curated by ChEMBL
LigandPNGBDBM50157884(6-(2-Mercapto-acetylamino)-hexanoic acid phenylami...)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50157884(6-(2-Mercapto-acetylamino)-hexanoic acid phenylami...)
Affinity DataIC50: 390nMAssay Description:Inhibitory concentration against histone deacetylase of HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50157884(6-(2-Mercapto-acetylamino)-hexanoic acid phenylami...)
Affinity DataIC50: 390nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50157884(6-(2-Mercapto-acetylamino)-hexanoic acid phenylami...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human HDAC8 incubated for 90 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed