BDBM50138674 6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-cyclopentyloxy-phenyl)-amide::6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE::6-carbamimidoyl-N-(3-(cyclopentyloxy)phenyl)-2-naphthamide::CHEMBL111575

SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1cccc(OC2CCCC2)c1

InChI Key InChIKey=FWTQOPWAMQXIMI-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50138674   

TargetUrokinase-type plasminogen activator(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138674(6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PH...)
Affinity DataKi:  25nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138674(6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PH...)
Affinity DataKi:  28nMAssay Description:Binding affinity to human urokinase-type plasminogen activator (microPa).More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138674(6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PH...)
Affinity DataKi:  56nMAssay Description:Binding affinity against porcine trypsin was determined.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138674(6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PH...)
Affinity DataKi:  498nMAssay Description:Binding affinity towards human plasmin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasma kallikrein(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138674(6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PH...)
Affinity DataKi:  2.72E+3nMAssay Description:Binding affinity against human plasma kallikrein.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTissue-type plasminogen activator(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138674(6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PH...)
Affinity DataKi:  3.39E+3nMAssay Description:Binding affinity towards human Tissue type plasminogen activator.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138674(6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PH...)
Affinity DataKi:  5.58E+3nMAssay Description:Binding affinity against human alpha thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed