BDBM50137276 6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide::CHEMBL148214::N,6-dihydroxy-7-methoxy-2-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide

SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2cc(O)c(OC)cc2C1C(=O)NO

InChI Key InChIKey=AYFCYVLVRYQGME-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50137276   

TargetMatrix metalloproteinase-9(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 68nMAssay Description:Inhibition of matrix metalloprotease-14 (MMP-14)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 123nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage metalloelastase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of matrix metalloprotease-12 (MMP-12)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of matrix metalloprotease-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-26(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 86nMAssay Description:Inhibition of matrix metalloprotease-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-15(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of matrix metalloprotease-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrilysin(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrilysin(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails Article
PubMed