BDBM50136755 CHEMBL3752386

SMILES COc1ccc(cc1)C1(CNC(=O)c2ccc(NC(=O)c3ccco3)cc2Cl)CCOCC1

InChI Key InChIKey=PFKDFLVWKSDYJO-UHFFFAOYSA-N

Data  13 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50136755   

TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ARTD1 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 360nMAssay Description:Inhibition of tankyrase in WNT3a-stimulated human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of human TNKS2 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 562nMAssay Description:Inhibition of human TNKS1 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of human TNKS2 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 570nMAssay Description:Inhibition of human TNKS1 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ARTD2 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ARTD3 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ARTD4 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ARTD7 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ARTD8 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ARTD10 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP12(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50136755(CHEMBL3752386)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ARTD12 by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed