BDBM50128062 (4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMINO]BUT-2-ENYL}OXY)PHENYL]METHANONE::(4-Bromo-phenyl)-{4-[4-(cyclopropyl-methyl-amino)-but-2-enyloxy]-phenyl}-methanone::CHEMBL479653::CHEMBL62855::N-(4-(4-(4-bromobenzoyl)phenoxy)but-2-enyl)-N-methylcyclopropanaminium

SMILES CN(C\C=C\COc1ccc(cc1)C(=O)c1ccc(Br)cc1)C1CC1

InChI Key InChIKey=JAZMZJDLZUDIDG-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50128062   

TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128062(CHEMBL62855 | (4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPRO...)
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene--hopene cyclase(Alicyclobacillus acidocaldarius)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128062(CHEMBL62855 | (4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPRO...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldariusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetLanosterol synthase ERG7(Baker's yeast)
Università

Curated by ChEMBL
LigandPNGBDBM50128062(CHEMBL62855 | (4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPRO...)
Affinity DataIC50: 180nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCycloartenol synthase(Mouse-ear cress)
Università

Curated by ChEMBL
LigandPNGBDBM50128062(CHEMBL62855 | (4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPRO...)
Affinity DataIC50: 260nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128062(CHEMBL62855 | (4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPRO...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128062(CHEMBL62855 | (4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPRO...)
Affinity DataIC50: 19.1nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed