BDBM50128058 ALLYL-{6-[3-(4-BROMO-PHENYL)-1-METHYL-1H-INDAZOL-6-YL]OXY}HEXYL)-N-METHYLAMINE::Allyl-{6-[3-(4-bromo-phenyl)-1-methyl-1H-indazol-6-yloxy]-hexyl}-methyl-amine::CHEMBL115497::CHEMBL66424::N-allyl-6-(3-(4-bromophenyl)-1-methyl-1H-indazol-6-yloxy)-N-methylhexan-1-aminium

SMILES CN(CCCCCCOc1ccc2c(nn(C)c2c1)-c1ccc(Br)cc1)CC=C

InChI Key InChIKey=FNZKIJOTNKEJBF-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50128058   

TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 19.6nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSqualene--hopene cyclase(Alicyclobacillus acidocaldarius)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 289nMAssay Description:Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldariusMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetLanosterol synthase ERG7(Baker's yeast)
Università

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 290nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCycloartenol synthase(Mouse-ear cress)
Università

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 19.6nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 19nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed