BDBM50122002 CHEMBL1383671

SMILES Nc1cnccc1C(O)=O

InChI Key InChIKey=FYEQKMAVRYRMBL-UHFFFAOYSA-N

Data  14 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50122002   

TargetD-amino-acid oxidase(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human recombinant DAO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD-aspartate oxidase(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4D(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of KDM4D (unknown origin) by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProlyl hydroxylase EGLN3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of full-length EGLN3 (unknown origin) expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4A(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 501nMAssay Description:Inhibition of KDM4A (unknown origin) by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 6B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of KDM6B (unknown origin) by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 631nMAssay Description:Inhibition of N-terminal his-tagged human KDM4C expressed in Escherichia coli BL21(DE3) using trimethylated peptide substrate by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4E(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of KDM4E (unknown origin) by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 631nMAssay Description:Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 6B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of human KDM6B catalytic domain using H3(20 to 36 residues)K27Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4D(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human KDM4D (11 to 341 residues) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectromet...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProlyl hydroxylase EGLN3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of full length His-MBP-att-EGLN3 (1 to 239 residues) (unknown origin) in Escherichia coli BL21(DE3)pRR692 cells assessed as hydroxylation ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLysine-specific demethylase 4C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 631nMAssay Description:Inhibition of KDM4C (unknown origin) measured by RapidFire mass spectrometry (RFMS)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetLysine-specific demethylase 4D(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of KDM4D (unknown origin) measured by RapidFire mass spectrometry (RFMS)More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)