BDBM50118952 2-Amino-3-methyl-1-pyrrolidin-1-yl-butan-1-one::CHEMBL16709::US9115082, 9

SMILES CC(C)C(N)C(=O)N1CCCC1

InChI Key InChIKey=IHBAVXVTGLANPI-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118952   

TargetDipeptidyl peptidase 4(Human)
TBA

US Patent
LigandPNGBDBM50118952(2-Amino-3-methyl-1-pyrrolidin-1-yl-butan-1-one | C...)
Affinity DataIC50: 548nMpH: 4.0Assay Description:The proteolytic enzyme, Dipeptidyle Peptidase IV (DppIV) was monitored in vitro by the substrate Gly-Pro 4-methoxy-β-naphthylamide while in the ...More data for this Ligand-Target Pair
In DepthDetails
US Patent
PDB3D3D Structure (crystal)
TargetDipeptidyl peptidase 2(Human)
University of Antwerp (Uia)

Curated by ChEMBL
LigandPNGBDBM50118952(2-Amino-3-methyl-1-pyrrolidin-1-yl-butan-1-one | C...)
Affinity DataIC50: 2.23E+5nMAssay Description:Inhibitory activity of compound against Dipeptidylpeptidase II (DPP II)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
TBA

US Patent
LigandPNGBDBM50118952(2-Amino-3-methyl-1-pyrrolidin-1-yl-butan-1-one | C...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against Dipeptidylpeptidase IV (DPP IV)More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetDipeptidyl peptidase IV(Porphyromonas gingivalis)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50118952(2-Amino-3-methyl-1-pyrrolidin-1-yl-butan-1-one | C...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Porphyromonas gingivalis N-terminal His-tagged DPP4 expressed in Escherichia coli using Gly-Pro-p-nitroanilide as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed