BDBM50113851 (+/-)-Tranylcypromine::2-PCPA::2-Phenyl-cyclopropylamine::2-phenylcyclopropanamine::CHEMBL313833::TRANYLCYPROMINE::Tranylcypromine,(+)::Tranylcypromine,(-)::US8609708, 6 Tranyl- cypromine::US8609708, 6 Tranylcypromine
SMILES NC1CC1c1ccccc1
InChI Key InChIKey=AELCINSCMGFISI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 49 hits for monomerid = 50113851
Affinity DataEC50: 2.70E+3nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of MAO-B (unknown origin) by MAo-Glo kit analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+5nMAssay Description:Irreversible inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant LSD1 assessed as effect on H2O2 production incubated for 30 mins using methylated peptide substrate, Amplex red reage...More data for this Ligand-Target Pair
Affinity DataIC50: 7.87E+3nMAssay Description:Inhibition of human MAOA using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazolecarboxylic acid substrate incubated for 60 mins by luciferin de...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human MAOB using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazolecarboxylic acid substrate incubated for 60 mins by luciferin de...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of N-terminal hexahistidine-tagged human LSD1 (1 to 852 amino acid residues) expressed in Escherichia coli BL21 (DE3) using H3K4me2 peptid...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human MAO-B using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazolecarboxylic acid as substrate after 60 mins by MAO-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human MAO-A using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazolecarboxylic acid as substrate after 60 mins by MAO-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MAO-A (unknown origin) by MAo-Glo kit analysisMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+6nMAssay Description:Inhibition of recombinant human LSD2 using H3K4 peptide as substrate assessed as decrease in H3K4 demethylation after 1 hr by mass spectroscopic anal...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MAOBMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected insect cells by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.72E+3nMAssay Description:Inhibition of MAOA (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of MAOB (unknown origin) using beetle luciferin as substrate by MAO-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length recombinant human LOXL2 expressed in CHO cells assessed as reduction in H2O2 production using DAP as substrate preincubated...More data for this Ligand-Target Pair
Affinity DataIC50: 2.93E+4nMAssay Description:Inhibition of recombinant LSD1 (157 to 852 amino acids) (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red...More data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.64E+3nMAssay Description:Inhibition of N-terminal His-tagged SARS-CoV-2 3CLpro by microplate reader assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human full length LSD2 using biotin-labeled H3K4me2 (1 to 24 residues) as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of human recombinant N-terminal His/GST-tagged LSD1 (172 to 852 residues) expressed in baculovirus infected insect cells using biotin-labe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected insect cells by luminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.84E+5nMAssay Description:The kinetic inhibition parameters of LSD1 demethylase inhibition were obtained using the peroxidase-coupled reaction method.More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
Affinity DataIC50: 970nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:The interaction of SC12 with cytochrome P450 enzymes was tested using Fluorescent High Throughput P450 assays (Gentest); The IC50s of the compounds w...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:The interaction of SC12 with cytochrome P450 enzymes was tested using Fluorescent High Throughput P450 assays (Gentest); The IC50s of the compounds w...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) using 7-ethoxy-3-cyanocoumarin as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human recombinant MAOB expressed in Pichia pastoris incubated for 15 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli assessed as reduction in H2O2 release using synthetic mono-methylated H3-K...More data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 20 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+5nMAssay Description:Inhibition of human recombinant LSD1 after 30 mins to 4 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.33E+4nMAssay Description:Binding affinity against bovine trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nMAssay Description:Inhibition of human LSD1 catalytic domainMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
Affinity DataKi: 2.43E+5nMAssay Description:Binding affinity to LSD1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair