BDBM50104501 (R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((S)-1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide::(R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((S)-1-dimethylcarbamoyl-2-methyl-2-methyl-propyl)-amide::(R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid (1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide::(R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid [1-((S)-dimethyl-carbamoyl)-2,2-dimethyl-propyl]-amide::2-[(FORMYL-HYDROXY-AMINO)-METHYL]-HEXANOIC ACID (1-DIMETHYLCARBAMOYL-2,2-DIMETHYL-PROPYL)-AMIDE::BB-3497::CHEMBL431210

SMILES CCCC[C@H](CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C

InChI Key InChIKey=AVDLWYHBABSSHC-UHFFFAOYSA-N

Data  1 KI  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50104501   

TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 7nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against Escherichia coli peptide deformylase (PDF) Nickel containing enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAngiotensin-converting enzyme(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeprilysin(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compound was evaluated in vitro for the inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptide deformylase, mitochondrial(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 7nMAssay Description:Antibacterial activity against Escherichia coli Peptide deformylase. NiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrilysin(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptide deformylase, mitochondrial(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 7nMAssay Description:Compound was evaluated for inhibition of peptide deformylase, PDF.Ni of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptide deformylase, mitochondrial(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 7nMAssay Description:Inhibition against Escherichia coli peptide deformylaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataIC50: 7nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptide deformylase(Escherichia coli)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501(BB-3497 | (R)-2-[(Formyl-hydroxy-amino)-methyl]-he...)
Affinity DataKi:  11nMAssay Description:Inhibitory effect against Escherichia coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed